Address: 563 2nd Ave, San Francisco CA 94107 / (415) 369-0900
About Us / 21st Amendment Pub & Brewery History: The 21st Amendment is a full service restaurant with bar open seven days a week for lunch and dinner and Sunday brunch. We are located in the SOMA area of San Francisco, just two blocks from the San Francisco Giants park. We serve casual grilled cuisine and our handcrafted beers and sodas. To us, the 21st Amendment means much more than just an end to Prohibition. It means the right to brew beer, the freedom to be innovative, and the obligation to have fun.